WebThe SIN mean IC50 for HGC-27, SGC-7901, and BGC-803 at 24 hours was 372.60, 284.40, and 279.70 μM; The cisplatin mean IC50 for HGC-27, SGC-7901, and BGC-803 at 24 hours was 3.85, 3.13, and... WebCisplatin (DDP) is a common therapeutic option for non-small cell lung carcinoma (NSCLC). However, some patients fail to respond to the DDP chemotherapy. Therefore, identifying novel biomarkers to improve the diagnosis and treatment of NSCLC is important.
Cisplatin (Intravenous Route) Side Effects - Mayo Clinic
WebDrug: Cisplatin - Cancerrxgene - Genomics of Drug Sensitivity in Cancer Genomics of Drug Sensitivity in Cancer Compound: Cisplatin Drug Target: DNA crosslinker Drug Target … STR profiles of cell lines Cell line authentication. Concerns around the … The IC50 and AUC are estimated using a non-linear mixed effect model fitting a … Users have a non-exclusive, non-transferable right to use data files for … WebA cisplatin-resistant cell subline, HeLa/CDDP cells, showed a 19-fold resistance to cisplatin compared with the parent cells. The subline showed a collateral sensitivity to … great reaction
Evaluation of anti-metastatic potential of Cisplatin polymeric ...
WebJun 5, 2024 · We first analyzed the correlation between TFEB expression and half maximal inhibitory concentration (IC50) of CDDP using Genomics of Drug Sensitivity in Cancer … WebThe DDP at a concentration of IC50 (AGS/DDP cells, 71.34 μM; MKN45/DDP cells, 61.28 μM) was used for further experiments. Bax and Bcl-2 are biomarkers of apoptosis. As illustrated in Figure 2E , the protein expression of Bax was remarkably elevated, while Bcl-2 was declined in AGS/DDP and MKN45/DDP cells following sh-HCG11 transfection or … WebPurpose: Alterations in the DNA mismatch repair (MMR) proteins have been associated with an increased resistance of many cancer cell lines to cisplatin. The aim of this work was … floor to ceiling headboard diy