WebCTCF. Transcriptional repressor CTCF also known as 11-zinc finger protein or CCCTC-binding factor is a transcription factor that in humans is encoded by the CTCF gene. [5] … WebAug 2, 2024 · EMSAs of 10 CTCF-binding sites containing a mutation, which we define here as variable regions, compared to a known CTCF-binding site along with the endogenous …
Predicting CTCF-mediated chromatin loops using CTCF-MP
WebNov 26, 2012 · This CTCF-binding sequence, which was identified in MCF-7 cells, overlaps binding sequences that were identified in four other cell types. ... Additionally, we included the position weight matrices of the M1 and M2 motifs in the CTCFBSDB Prediction Tool, which has been described previously , allowing users to scan query sequences for CTCF ... WebDec 23, 2008 · The mechanism underlying enhancer-blocking by insulators is unclear. We explored the activity of human β-globin HS5, the orthologue of the CTCF-dependent chicken HS4 insulator. An extra copy of HS5 placed between the β-globin locus control region (LCR) and downstream genes on a transgene fulfills the classic predictions for an enhancer … china 1 buffet big rapids mi
Prediction and Comparative Analysis of CTCF Binding …
WebAug 1, 2013 · CTCF sites were classified as eQTL interrupting if the midpoint of the CTCF binding site was between the eQTL SNP and the TSS of the associated gene. To test if … WebDec 6, 2024 · HiC-Reg predictions identify topologically associating domains and significant interactions that are enriched for CCCTC-binding factor (CTCF) bidirectional motifs and interactions identified from ... WebMar 12, 2024 · The permutation importance of CTCF predictions in PANC-1 is 0.27, while the permutation importance of CTCF predictions in IMR-90 is 0.15. The variation in correlation of similarity to training cell types and permutation importance of the expression score is more evident for REST . While the median similarity of REST binding with … china 1 buffet menu pigeon forge tn